English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

The extracellular matrix of the spleen as a potential organizer of immune cell compartments

MPS-Authors
/persons/resource/persons204285

Lämmermann,  Tim
Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

Fulltext (public)

Lokmic et al 2008.pdf
(Publisher version), 2MB

Supplementary Material (public)
There is no public supplementary material available
Citation

Lokmic, Z., Lämmermann, T., Sixt, M., Cardell, S., Hallmann, R., & Sorokin, L. (2008). The extracellular matrix of the spleen as a potential organizer of immune cell compartments. Seminars in Immunology, 20, 4-13. doi:10.1016/j.smim.2007.12.009.


Cite as: http://hdl.handle.net/21.11116/0000-0007-74AA-7
Abstract
Until recently little information was available on the molecular details of the extracellular matrix (ECM) of secondary lymphoid tissues. There is now growing evidence that these ECMs are unique structures, combining characteristics of basement membranes and interstitial or fibrillar matrices, resulting in scaffolds that are strong and highly flexible and, in certain secondary lymphoid compartments, also forming conduit networks for rapid fluid transport. This review will address the structural characteristics of the ECM of the murine spleen and its potential role as an organizer of immune cell compartments, with reference to the lymph node where relevant.