A Model of Oscillatory Protein Dynamics in Bacteria

Rashkov, P.; Schmitt, B. A.; Sogaard-Andersen, L.; Lenz, P.; Dahlke, S.

doi:10.1007/s11538-012-9752-y

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

A Model of Oscillatory Protein Dynamics in Bacteria

MPS-Authors

/persons/resource/persons254723

Sogaard-Andersen, L.
Bacterial Adaption and Differentiation, Department of Ecophysiology, Max Planck Institute for Terrestrial Microbiology, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Rashkov, P., Schmitt, B. A., Sogaard-Andersen, L., Lenz, P., & Dahlke, S. (2012). A Model of Oscillatory Protein Dynamics in Bacteria. Bulletin of Mathematical Biology, 74(9), 2183-2203. doi:10.1007/s11538-012-9752-y.

Cite as: https://hdl.handle.net/21.11116/0000-0007-C089-5

Abstract

Spatial oscillations of proteins in bacteria have recently attracted much attention. The cellular mechanism underlying these oscillations can be studied at molecular as well as at more macroscopic levels. We construct a minimal mathematical model with two proteins that is able to produce self-sustained regular pole-to-pole oscillations without having to take into account molecular details of the proteins and their interactions. The dynamics of the model is based solely on diffusion across the cell body and protein reactions at the poles, and is independent of stimuli coming from the environment. We solve the associated system of reaction-diffusion equations and perform a parameter scan to demonstrate robustness of the model for two possible sets of the reaction functions.