English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

The AGC Ser/Thr kinase Aga1 is essential for appressorium formation and maintenance of the actin cytoskeleton in the smut fungus Ustilago maydis

MPS-Authors
/persons/resource/persons254135

Berndt,  P.
Department of Organismic Interactions, Alumni, Max Planck Institute for Terrestrial Microbiology, Max Planck Society;

/persons/resource/persons254478

Lanver,  D.
Department of Organismic Interactions, Alumni, Max Planck Institute for Terrestrial Microbiology, Max Planck Society;

/persons/resource/persons254413

Kahmann,  R.
Emeriti Molecular Phytopathology, Max Planck Institute for Terrestrial Microbiology, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Berndt, P., Lanver, D., & Kahmann, R. (2010). The AGC Ser/Thr kinase Aga1 is essential for appressorium formation and maintenance of the actin cytoskeleton in the smut fungus Ustilago maydis. Molecular Microbiology, 78(6), 1484-1499. doi:10.1111/j.1365-2958.2010.07422.x.


Cite as: https://hdl.handle.net/21.11116/0000-0007-C2F9-5
Abstract
On the plant surface the dimorphic fungus Ustilago maydis switches from budding to hyphal growth and differentiates appressoria. To get more insight into these highly regulated processes we report on the role of a conserved Ser/Thr kinase of the AGC kinase family, Aga1. U. maydis Aga1 could functionally replace Ypk1p in Saccharomyces cerevisiae. aga1 deletion mutants were affected in growth, cell wall integrity, mating as well as the ability to form appressoria and showed defects in actin organization and actin-dependent endocytosis. With respect to appressorium formation and endocytosis, the aga1 deletion phenotype could be mimicked by inhibiting the formation of actin filaments with Latrunculin A. These data suggest a critical role of Aga1 in F-actin organization during the morphological changes accompanying the development of appressoria.