The cGMP-gated channel of rod outer segments is not localized in bipolar cells 
of the mammalian retina

Wässle, Heinz; Grünert, Ulrike; Cook, Neil J.; Molday, Robert S.

doi:10.1016/0304-3940(92)90516-A

アイテム詳細

登録内容を編集ファイル形式で保存

一時保存へ追加

タグ情報を表示リリース履歴を表示詳細要約

公開

学術論文

The cGMP-gated channel of rod outer segments is not localized in bipolar cells of the mammalian retina

MPS-Authors

/persons/resource/persons208268

Wässle, Heinz
Neuroanatomy Department, Max Planck Institute for Brain Research, Max Planck Society;

Grünert, Ulrike
Neuroanatomy Department, Max Planck Institute for Brain Research, Max Planck Society;

/persons/resource/persons252599

Cook, Neil J.
Department of Molecular Membrane Biology, Max Planck Institute of Biophysics, Max Planck Society;

External Resource

There are no locators available

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

フルテキスト (公開)

公開されているフルテキストはありません

付随資料 (公開)

There is no public supplementary material available

引用

Wässle, H., Grünert, U., Cook, N. J., & Molday, R. S. (1992). The cGMP-gated channel of rod outer segments is not localized in bipolar cells of the mammalian retina. Neuroscience Letters, 134(2), 199-202. doi:10.1016/0304-3940(92)90516-A.

引用: https://hdl.handle.net/21.11116/0000-0007-A08A-8

要旨

It has recently been suggested (Nature, 346 (1990) 269–271) that ON-bipolar cells express the same biochemical cascade and guanosine 3′,5′-cyclic monophosphate (cGMP)-gated cation channel as rod outer segments. An antibody directed against the cGMP-gated channel of bovine rod outer segments was applied to cryostat sections of rat and cat retinae. No immunocytochemical labelling was found in bipolar cells. Therefore, if those cells express a cGMP-gated channel, it must be immunologically different to the 63 kDa protein constituting the cGMP-gated channel of the outer segment.