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Anion transport in red blood cells and arginine specific reagents. (1) Effect of chloride and sulfate ions on phenylglyoxal sensitive sites in the red blood cell membrane

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Zaki,  Laila
Department of Cell Physiology, Max Planck Institute of Biophysics, Max Planck Society;

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Zaki, L. (1983). Anion transport in red blood cells and arginine specific reagents. (1) Effect of chloride and sulfate ions on phenylglyoxal sensitive sites in the red blood cell membrane. Biochemical and Biophysical Research Communications, 110(2), 616-624. doi:10.1016/0006-291X(83)91194-4.


Cite as: http://hdl.handle.net/21.11116/0000-0007-DDF5-C
Abstract
Inhibition of anion transport by the arginine specific reagents phenylglyoxal and 1,2 cyclohexandione depends on the pH and anion concentration in the medium. At pH 8.0, chloride ions protect the transport system against inhibition by PG and 1,2 CHD, while sulfate ions do not protect (1). In the present paper it is shown that at pH 6.5 and 7 both sulfate ions and chloride ions protect the transport system. The protection increases with increasing concentration of the two substrate ions.