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Conference Paper

Towards a cellular genealogy ontology

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Burek, P., Herre, H., Roeder, I., Glauche, I., Scherf, N., & Löffler, M. (2010). Towards a cellular genealogy ontology. In Proceedings of the OBML 2010 Workshop.

Cite as: https://hdl.handle.net/21.11116/0000-0007-CF40-8
In the present paper we outline basic ideas and results about a Cellular Genealogy Ontology (CGO). This work is aimed at providing a framework for analyzing, spec-ifying and annotating results of experiments and of simula-tions in the field of stem cell research. The real world ob-jects of these investigations are processual cellular genealo-gies which are studied by using, among other methods, time lapse experiments. This framework pursues three goals: Firstly, it provides a domain independent core ontology, called Simple Process Object Ontology (SPOO). SPOO is the basis for a coherent and integrative handling of objects, processes and characteristics which are the main building blocks for any domain ontology. Secondly, this core ontol-ogy is utilized for the development of a domain ontology for cellular genealogies. Thirdly, this domain ontology CGO is intended to support and enrich tracking algorithms by providing annotations of photos, storage and structuring of analysis results, and, thus, enables the discovery of correla-tions between qualities, visualizations of annotations. Fur-thermore, CGO is intended to support semantically correct data exchange (import, export).