English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Molecular hydrogen (H2) as a potential treatment for acute and chronic fatigue

MPS-Authors
/persons/resource/persons187669

Lucas,  Kurt
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons256142

Rosch,  Moritz
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

External Resource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Lucas, K., Rosch, M., & Langguth, P. (2020). Molecular hydrogen (H2) as a potential treatment for acute and chronic fatigue. Archiv der Pharmazie, e2000378. doi:10.1002/ardp.202000378.


Cite as: http://hdl.handle.net/21.11116/0000-0007-D3A6-F
Abstract
Many diseases as well as acute conditions can lead to fatigue, which can be either temporary or chronic in nature. Acute fatigue develops frequently after physical exercise or after alcohol hangover, whereas microbial infections such as influenza or COVID‐19 and chronic diseases like Parkinson's disease or multiple sclerosis are often associated with chronic fatigue. Oxidative stress and a resulting disturbance of mitochondrial function are likely to be common denominators for many forms of fatigue, and antioxidant treatments have been shown to be effective in alleviating the symptoms of fatigue. In this study, we review the role of reactive oxygen and nitrogen species in fatigue and the antioxidant effects of the intake of molecular hydrogen. We propose that molecular hydrogen is well suited for the treatment of temporary and chronic forms of oxidative stress‐associated fatigue.