English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

Sugar transport by renal plasma membrane vesicles. Characterization of the systems in the brush-border microvilli and basal-lateral plasma membranes

MPS-Authors
/persons/resource/persons257977

Kinne,  Rolf
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;
Laboratory of Membrane Biology, University of Alabama, 35294, Birmingham, Alabama;

/persons/resource/persons257975

Murer,  Heini
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;
Laboratory of Membrane Biology, University of Alabama, 35294, Birmingham, Alabama;

/persons/resource/persons257981

Kinne-Saffran,  Evamaria
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;
Laboratory of Membrane Biology, University of Alabama, 35294, Birmingham, Alabama;

/persons/resource/persons257983

Thees,  M.
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;
Laboratory of Membrane Biology, University of Alabama, 35294, Birmingham, Alabama;

/persons/resource/persons257985

Sachs,  George
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Kinne, R., Murer, H., Kinne-Saffran, E., Thees, M., & Sachs, G. (1975). Sugar transport by renal plasma membrane vesicles. Characterization of the systems in the brush-border microvilli and basal-lateral plasma membranes. Journal of Membrane Biology, 21, 375-395. doi:10.1007/BF01941077.


Cite as: https://hdl.handle.net/21.11116/0000-0009-BE61-4
Abstract
Uptake studies ofD- andL-glucose were performed on vesicles derived from brush-border and basal-lateral membranes. The uptake of the sugars into the vesicles was osmotically sensitive and independent of glucose metabolism. In brush-border vesiclesD-glucose but notL-glucose transport was Na+-dependent, was inhibited by phlorizin, and showed a transitory vesicle/medium ratio >1, in the presence of an initial Na+ gradient. Basal-lateral membranes take upD-glucose faster thanL-glucose, but theD-glucose uptake is significantly less sensitive to sodium removal and only moderately inhibited by phlorizin as compared to the brush-border fraction.