Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection

Wettstein, Lukas; Weil, Tanja; Conzelmann, Carina; Müller, Janis A.; Gross, Rüdiger; Hirschenberger, Maximilian; Seidel, Alina; Klute, Susanne; Zech, Fabian; Bozzo, Caterina Prelli; Preising, Nico; Fois, Giorgio; Lochbaum, Robin; Knaff, Philip Maximilian; Mailänder, Volker; Staendker, Ludger; Thal, Dietmar Rudolf; Schumann, Christian; Stenger, Steffen; Kleger, Alexander; Lochnit, Günter; Mayer, Benjamin; Ruiz-Blanco, Yasser B.; Hoffmann, Markus; Sparrer, Konstantin M. J.; Poehlmann, Stefan; Sanchez-Garcia, Elsa; Kirchhoff, Frank; Frick, Manfred; Muench, Jan

doi:10.1038/s41467-021-21972-0

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Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection

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Knaff, Philip Maximilian
Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Dermatol, Mainz, Germany;
Dept. Landfester: Physical Chemistry of Polymers, MPI for Polymer Research, Max Planck Society;

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Mailänder, Volker
Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Dermatol, Mainz, Germany;
Dept. Landfester: Physical Chemistry of Polymers, MPI for Polymer Research, Max Planck Society;

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Wettstein, L., Weil, T., Conzelmann, C., Müller, J. A., Gross, R., Hirschenberger, M., et al. (2021). Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection. Nature Communications, 12: 1726. doi:10.1038/s41467-021-21972-0.

Cite as: https://hdl.handle.net/21.11116/0000-0008-400B-4

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