Chromatographic isolation and characterization of streptogramin antibiotics

Grell, Ernst; Lewitzki, Erwin; Dehal, S.; Oberbäumer, Ilse; Raschdorf, F.; Richter, W.J.

doi:10.1016/S0021-9673(01)93560-5

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Chromatographic isolation and characterization of streptogramin antibiotics

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Grell, Ernst
Molecular Biophysics Group, Max Planck Institute of Biophysics, Max Planck Society;

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Lewitzki, Erwin
Molecular Biophysics Group, Max Planck Institute of Biophysics, Max Planck Society;

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Dehal, S.
Molecular Biophysics Group, Max Planck Institute of Biophysics, Max Planck Society;

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Oberbäumer, Ilse
Molecular Biophysics Group, Max Planck Institute of Biophysics, Max Planck Society;

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Citation

Grell, E., Lewitzki, E., Dehal, S., Oberbäumer, I., Raschdorf, F., & Richter, W. (1984). Chromatographic isolation and characterization of streptogramin antibiotics. Journal of Chromatography A, 290, 57-63. doi:10.1016/S0021-9673(01)93560-5.

Cite as: https://hdl.handle.net/21.11116/0000-0008-69BA-1

Abstract

High-performance and medium-pressure liquid chromatographic techniques were developed for the rapid isolaiton, identification and characterization of the components from crude virginiamycin and viridogrisein. Two new minor components, denoted virginiamycin S₅ and viridogrisein II, were isolated. Their structures were determined by amino acids analysis and mass spectrometry. (I. Oberbäumer et al., Helv. Chim. Acta, 65 (1982) 2280).