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Investigating layer specific MR properties in the superior colliculus ex vivo at 14.1T

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Lee,  JY
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Hagberg,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Lee, J., Mack, A., Shiozawa-Bayer, T., Himmelbach, M., Hagberg, G., & Scheffler, K. (2021). Investigating layer specific MR properties in the superior colliculus ex vivo at 14.1T. Poster presented at 2021 ISMRM & SMRT Annual Meeting & Exhibition (ISMRM 2021).


Cite as: http://hdl.handle.net/21.11116/0000-0008-86CB-C
Abstract
Layer specific MR properties have previously been observed in the superior colliculus in vivo at 9.4T. The present study investigates layer specific MR properties in R2* and R1 in more detail in post mortem brain stem samples at 14.1T. Similar to in vivo, one R2* maximum that likely corresponds to the superficial optic layer (layer III) was observed. Ex vivo we could observe high R2* and R1 in an area likely corresponding to the deep white layer (layer VII) of the superior colliculus. In the R1maps, this area showed a strong contrast towards the periaqueductal gray.