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Meeting Abstract

Mapping of Thalamic Matrix and Core Nuclei using QSM at 9.4 Tesla

MPS-Authors
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Kumar,  VJ
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Hagberg,  GE
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Grodd,  W
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Kumar, V., Scheffler, K., Hagberg, G., & Grodd, W. (2021). Mapping of Thalamic Matrix and Core Nuclei using QSM at 9.4 Tesla. In 2021 ISMRM & SMRT Annual Meeting & Exhibition (ISMRM 2021).


Cite as: https://hdl.handle.net/21.11116/0000-0008-900F-5
Abstract
The thalamus is a central connectivity hub of the human brain that remains poorly understood concerning its anatomy. Since it houses both calcium-rich neurons and myelin-rich architecture, quantitative susceptibility mapping at the ultra-high-field may facilitate thalamic substructures' characterization. Consequently, we have acquired high-resolution QSM data at 9.4 Tesla in 21 subjects and analyzed human thalamic nuclei with respect to core and matrix neurons. We found a more substantial contribution of both diamagnetic and paramagnetic sources, like iron, myelin, and calcium, in the matrix nuclei in contrast to the relay specific core nuclei matrix nuclei.