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Meeting Abstract

Inductively coupled detectors for optogenetic-driven focal and multiregional fMRI signal enhancement

MPG-Autoren
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Chen,  Y
Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Wang,  Q
Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Zeng,  H
Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Takahashi,  K
Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Choi,  S
Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Yu,  X
Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

Externe Ressourcen

https://www.ismrm.org/21/program-files/O-72.htm
(Zusammenfassung)

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Zitation

Chen, Y., Wang, Q., Zeng, H., Takahashi, K., Choi, S., Qian, C., et al. (2021). Inductively coupled detectors for optogenetic-driven focal and multiregional fMRI signal enhancement. In 2021 ISMRM & SMRT Annual Meeting & Exhibition (ISMRM 2021).


Zitierlink: https://hdl.handle.net/21.11116/0000-0008-91C1-9
Zusammenfassung
To improve MR detection sensitivity of multi-modal fMRI platform, we present inductive coil which could relay locally detected MR signals to the external surface coil. Under sensory stimulation, evoked whole brain EPI-based fMRI and enhanced focal laminar-specific fMRI signals were acquired with high spatiotemporal resolution (100 μm and 100 ms) using a single experimental setup. Moreover, embedding inductive coil beneath the glue-secured optical fiber and the projection-mirrored cortex on the other hemisphere boosted multiregional fMRI sensitivity to investigate the interhemispheric connectivity with laminar-specificity. This is particularly helpful to study the optogenetic-driven brain connectivity with circuit specificity at multi-modal fMRI platform.