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Journal Article

A genome alignment of 120 mammals highlights ultraconserved element variability and placenta-associated enhancers.

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Hecker,  Nikolai
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Hiller,  Michael
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Hecker, N., & Hiller, M. (2020). A genome alignment of 120 mammals highlights ultraconserved element variability and placenta-associated enhancers. GigaScience, 9(1): giz159. doi:10.1093/gigascience/giz159.


Cite as: https://hdl.handle.net/21.11116/0000-0008-A23E-C
Abstract
Multiple alignments of mammalian genomes have been the basis of many comparative genomic studies aiming at annotating genes, detecting regions under evolutionary constraint, and studying genome evolution. A key factor that affects the power of comparative analyses is the number of species included in a genome alignment.