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Journal Article

Drops and fibers - how biomolecular condensates and cytoskeletal filaments influence each other.

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Wiegand,  Tina
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Hyman,  Anthony
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Wiegand, T., & Hyman, A. (2020). Drops and fibers - how biomolecular condensates and cytoskeletal filaments influence each other. Emerging topics in life sciences, 4(3), 247-261. doi:10.1042/ETLS20190174.


Cite as: https://hdl.handle.net/21.11116/0000-0008-A29C-1
Abstract
The cellular cytoskeleton self-organizes by specific monomer-monomer interactions resulting in the polymerization of filaments. While we have long thought about the role of polymerization in cytoskeleton formation, we have only begun to consider the role of condensation in cytoskeletal organization. In this review, we highlight how the interplay between polymerization and condensation leads to the formation of the cytoskeleton.