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Einfluß von Aldosteron auf den Ausstrom markierten Natriums aus den Sammelrohren der Ratte / Influence of aldosterone on 24Na-efflux in collecting ducts of rats

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Uhlich,  Eike
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;
Medizinische Universitäts-Poliklinik und Medizinische Klinik, Köln-Merheim, Federal Republic of Germany;

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Halbach,  Regine
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;
Medizinische Universitäts-Poliklinik und Medizinische Klinik, Köln-Merheim, Federal Republic of Germany;

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Ullrich,  Karl Julius
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;

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Citation

Uhlich, E., Halbach, R., & Ullrich, K. J. (1970). Einfluß von Aldosteron auf den Ausstrom markierten Natriums aus den Sammelrohren der Ratte / Influence of aldosterone on 24Na-efflux in collecting ducts of rats. Pflügers Archiv: European Journal of Physiology, 320, 261-264. doi:10.1007/BF00587457.


Cite as: http://hdl.handle.net/21.11116/0000-0008-B024-8
Abstract
In previous micropuncture studies with collecting ducts from the rat kidney, aldosterone was shown to increase the isotonic sodium reabsorption as well as the transepithelial concentration difference for sodium under steady state conditions with zero net flux. It was thought that the latter effect might have been partially due to a reduced leak permeability for sodium caused by the action of the hormone. To examine this possibility, the 24Na efflux from the collecting duct was studied and found to be decreased by aldosterone. It follows that the hormone must cause a substantial decrease in sodium permeability.