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Enzymaktivitäten im isolierten proximalen Tubulus der Kaninchenniere / Enzyme activities in the isolated proximal tubule of rabbit kidney

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Höhmann,  Bernhard
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;

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Zwiebel,  Ralf
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;

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Yamagata,  Akifusa
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;

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Kinne,  Rolf
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;

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Citation

Höhmann, B., Zwiebel, R., Yamagata, A., & Kinne, R. (1969). Enzymaktivitäten im isolierten proximalen Tubulus der Kaninchenniere / Enzyme activities in the isolated proximal tubule of rabbit kidney. Pflügers Archiv: European Journal of Physiology, 312, 110-125. doi:10.1007/BF00588536.


Cite as: https://hdl.handle.net/21.11116/0000-0008-B83B-7
Abstract
Activities of glutamate dehydrogenase (EC 1.4.1.2), succinate dehydrogenase (EC 1.3.99.1) and fumarase (EC 4.2.1.2) were determined in isolated segments of proximal tubules of the rabbit kidney. Activities per tubular length were the same at the beginning and the end of the pars convoluta. They decreased gradually along the pars recta towards the beginning of the thin loop of Henle. Thus, the capacity to produce energy via the Krebs cycle will be much lower in the pars recta than in the pars convoluta, a finding which parallels the different rates of sodium reabsorption along the isolated proximal tubule reported by Burg and Orloff.