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Journal Article

Salamander-Eci: An optical clearing protocol for the three-dimensional exploration of regeneration.

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Yun,  Maximina H
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Adrados, C. S., Yu, Q., Castro, L. A. B., Cabrera, L. A. R., & Yun, M. H. (2021). Salamander-Eci: An optical clearing protocol for the three-dimensional exploration of regeneration. Developmental dynamics: an official publication of the American Association of Anatomists, 250(6), 902-915. doi:10.1002/dvdy.264.


Cite as: https://hdl.handle.net/21.11116/0000-0008-DB03-E
Abstract
Salamander limb regeneration is a complex biological process that entails the orchestration of multiple cellular and molecular mechanisms in a three-dimensional space. Hence, a comprehensive understanding of this process requires whole-structure level explorations. Recent advances in imaging and optical clearing methods have transformed the study of regenerative phenomena, allowing the three-dimensional visualization of structures and entire organisms.