Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the 
Protein-RNA Interaction of LIN28 and Let-7

Borgelt, Lydia; Li, Fu; Hommen, Pascal; Lampe, Philipp; Hwang, Jimin; Goebel, Georg L.; Sievers, Sonja; Wu, Peng

doi:10.1021/acsmedchemlett.0c00546

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Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein-RNA Interaction of LIN28 and Let-7

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Borgelt, Lydia
Chemical Genomics Center of the MPS, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons127617

Li, Fu
Chemical Genomics Center of the MPS, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons251422

Hommen, Pascal
Chemical Genomics Center of the MPS, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons256986

Lampe, Philipp
Compound Management and Screening Center (COMAS), Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons251184

Hwang, Jimin
Chemical Genomics Center of the MPS, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons263547

Goebel, Georg L.
Chemical Genomics Center of the MPS, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons118736

Sievers, Sonja
Compound Management and Screening Center (COMAS), Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons241355

Wu, Peng
Chemical Genomics Center of the MPS, Max Planck Institute of Molecular Physiology, Max Planck Society;

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Borgelt, L., Li, F., Hommen, P., Lampe, P., Hwang, J., Goebel, G. L., et al. (2021). Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein-RNA Interaction of LIN28 and Let-7. ACS Medicinal Chemistry Letters, 12(6), 893-898. doi:10.1021/acsmedchemlett.0c00546.

Cite as: https://hdl.handle.net/21.11116/0000-0008-E1C0-0

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