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Journal Article

Versatile supplement device with remote control for the control of patch clamp experiments

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Gögelein,  Heinz
Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society;

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Citation

Rohlicek, V., Fröbe, U., Gögelein, H., & Greger, R. (1989). Versatile supplement device with remote control for the control of patch clamp experiments. Pflügers Archiv: European Journal of Physiology, 413, 444-446. doi:10.1007/BF00584498.


Cite as: https://hdl.handle.net/21.11116/0000-0008-E421-1
Abstract
A versatile device for a patch-clamp amplifier is described. This device contains: (i) an acoustic indicator to monitor the input resistance of the patch pipette, which is used in search-mode to indicate the formation of seals; (ii) two pulse generators; and (iii) a staircase generator to produce various pulse and voltage step programs; (iv) a lowpass filter which is used to filter the output of the patch clamp amplifier; and (v) a remote control which is used to control the entire patch clamp experiment. This remote control is used to switch between search-, current clamp-, and voltage clamp-mode, to activate the respective stimulus potential programs, and to control the tape recorder. This electronic device can be easily connected to patch clamp amplifiers.