English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Bioinspired functionally graded composite assembled using cellulose nanocrystals and genetically engineered proteins with controlled biomineralization

MPS-Authors
/persons/resource/persons121980

Wagermaier,  Wolfgang
Wolfgang Wagermaier, Biomaterialien, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)

Article.pdf
(Publisher version), 5MB

Supplementary Material (public)
There is no public supplementary material available
Citation

Mohammadi, P., Gandier, J.-A., Nonappa, Wagermaier, W., Miserez, A., & Penttilä, M. (2021). Bioinspired functionally graded composite assembled using cellulose nanocrystals and genetically engineered proteins with controlled biomineralization. Advanced Materials, 33(42): 2102658. doi:10.1002/adma.202102658.


Cite as: https://hdl.handle.net/21.11116/0000-0009-1FFA-C
Abstract
Nature provides unique insights into design strategies evolved by living organisms to construct robust materials with a combination of mechanical properties that are challenging to replicate synthetically. Hereby, inspired by the impact-resistant dactyl club of the stomatopod, a mineralized biocomposite is rationally designed and produced in the complex shapes of dental implant crowns exhibiting high strength, stiffness, and fracture toughness. This material consists of an expanded helicoidal organization of cellulose nanocrystals (CNCs) mixed with genetically engineered proteins that regulate both binding to CNCs and in situ growth of reinforcing apatite crystals. Critically, the structural properties emerge from controlled self-assembly across multiple length scales regulated by rational engineering and phase separation of the protein components. This work replicates multiscale biomanufacturing of a model biological material and also offers an innovative platform to synthesize multifunctional biocomposites whose properties can be finely regulated by colloidal self-assembly and engineering of its constitutive protein building blocks.