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Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure–Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo Studies

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Räder,  Hans Joachim
Dept. Weil: Synthesis of Macromolecules, MPI for Polymer Research, Max Planck Society;

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Jung, S., Fuchs, N., Johe, P., Wagner, A., Diehl, E., Yuliani, T., et al. (2021). Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure–Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo Studies. Journal of Medicinal Chemistry, 64(16), 12322-12358. doi:10.1021/acs.jmedchem.1c01002.


Cite as: http://hdl.handle.net/21.11116/0000-0009-2DA2-E
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