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Journal Article

Fast and sensitive taxonomic assignment to metagenomic contigs

MPS-Authors
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Mirdita,  M.
Research Group of Quantitative and Computational Biology, MPI for Biophysical Chemistry, Max Planck Society;

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Söding,  J.
Research Group of Quantitative and Computational Biology, MPI for Biophysical Chemistry, Max Planck Society;

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Levy Karin,  E.
Research Group of Quantitative and Computational Biology, MPI for Biophysical Chemistry, Max Planck Society;

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3348010.pdf
(Publisher version), 590KB

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Citation

Mirdita, M., Steinegger, M., Breitwieser, F., Söding, J., & Levy Karin, E. (2021). Fast and sensitive taxonomic assignment to metagenomic contigs. Bioinformatics, 37(18), 3029-3031. doi:10.1093/bioinformatics/btab184.


Cite as: https://hdl.handle.net/21.11116/0000-0009-6863-3
Abstract
MMseqs2 taxonomy is a new tool to assign taxonomic labels to metagenomic contigs. It extracts all possible protein fragments from each contig, quickly retains those that can contribute to taxonomic annotation, assigns them with robust labels and determines the contig’s taxonomic identity by weighted voting. Its fragment extraction step is suitable for the analysis of all domains of life. MMseqs2 taxonomy is 2–18× faster than state-of-the-art tools and also contains new modules for creating and manipulating taxonomic reference databases as well as reporting and visualizing taxonomic assignments.