Elimination versus mitigation of SARS-CoV-2 in the presence of effective 
vaccines

Oliu-Barton, Miquel; Pradelski, Bary S R; Algan, Yann; Baker, Michael G; Binagwaho, Agnes; Dore, Gregory J; El-Mohandes, Ayman; Fontanet, Arnaud; Peichl, Andreas; Priesemann, Viola; Wolff, Guntram B; Yamey, Gavin; Lazarus, Jeffrey V

doi:10.1016/S2214-109X(21)00494-0

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Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccines

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Priesemann, Viola
Max Planck Research Group Neural Systems Theory, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

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Citation

Oliu-Barton, M., Pradelski, B. S. R., Algan, Y., Baker, M. G., Binagwaho, A., Dore, G. J., et al. (2022). Elimination versus mitigation of SARS-CoV-2 in the presence of effective vaccines. The Lancet Global Health, 10, e142-e147. doi:10.1016/S2214-109X(21)00494-0.

Cite as: https://hdl.handle.net/21.11116/0000-0009-7440-C

Abstract

There is increasing evidence that elimination strategies have resulted in better outcomes for public health, the
economy, and civil liberties than have mitigation strategies throughout the first year of the COVID-19 pandemic. With
vaccines that offer high protection against severe forms of COVID-19, and increasing vaccination coverage, policy
makers have had to reassess the trade-offs between different options. The desirability and feasibility of eliminating
SARS-CoV-2 compared with other strategies should also be re-evaluated from the perspective of different fields,
including epidemiology, public health, and economics. To end the pandemic as soon as possible—be it through
elimination or reaching an acceptable endemic level—several key topics have emerged centring around coordination,
both locally and internationally, and vaccine distribution. Without coordination it is difficult if not impossible to sustain
elimination, which is particularly relevant in highly connected regions, such as Europe. Regarding vaccination,
concerns remain with respect to equitable distribution, and the risk of the emergence of new variants of concern.
Looking forward, it is crucial to overcome the dichotomy between elimination and mitigation, and to jointly define a
long-term objective that can accommodate different political and societal realities.