English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes

MPS-Authors
/persons/resource/persons239489

Neumann,  Gunnar U.
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;

/persons/resource/persons222993

Tukhbatova,  Rezeda I.
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;

/persons/resource/persons72801

Krause,  Johannes
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;

External Resource

Additional file 1
(Supplementary material)

Additional file 2
(Supplementary material)

Additional file 3
(Supplementary material)

Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)

shh3077.pdf
(Publisher version), 3MB

Supplementary Material (public)
There is no public supplementary material available
Citation

Pfrengle, S., Neukamm, J., Guellil, M., Keller, M., Molak, M., Avanzi, C., et al. (2021). Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes. BMC Biology, 19(1): 220. doi:10.1186/s12915-021-01120-2.


Cite as: https://hdl.handle.net/21.11116/0000-0009-79CC-A
Abstract
Hansen’s disease (leprosy), widespread in medieval Europe, is today mainly prevalent in tropical and subtropical regions with around 200,000 new cases reported annually. Despite its long history and appearance in historical records, its origins and past dissemination patterns are still widely unknown. Applying ancient DNA approaches to its major causative agent, Mycobacterium leprae, can significantly improve our understanding of the disease’s complex history. Previous studies have identified a high genetic continuity of the pathogen over the last 1500 years and the existence of at least four M. leprae lineages in some parts of Europe since the Early Medieval period.