Functional ultrasound imaging of the brain

Macé, Emilie; Montaldo, G.; Cohen, I.; Baulac, M.; Fink, Mathias; Tanter, M.

doi:10.1038/nmeth.1641

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Functional ultrasound imaging of the brain

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Macé, E., Montaldo, G., Cohen, I., Baulac, M., Fink, M., & Tanter, M. (2011). Functional ultrasound imaging of the brain. Nature Methods, 8(8), 662-664. doi:10.1038/nmeth.1641.

Cite as: https://hdl.handle.net/21.11116/0000-0009-B0FC-4

Abstract

We present functional ultrasound (fUS), a method for imaging transient changes in blood volume in the whole brain at better spatiotemporal resolution than with other functional brain imaging modalities. fUS uses plane-wave illumination at high frame rate and can measure blood volumes in smaller vessels than previous ultrasound methods. fUS identifies regions of brain activation and was used to image whisker-evoked cortical and thalamic responses and the propagation of epileptiform seizures in the rat brain.