Insect-Specific Production of New GameXPeptides in Photorhabdus luminescens 
TTO1, Widespread Natural Products in Entomopathogenic Bacteria

Nollmann, Friederike I.; Dauth, Christina; Mulley, Geraldine; Kegler, Carsten; Kaiser, Marcel; Waterfield, Nick R.; Bode, Helge B.

doi:10.1002/cbic.201402603

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Insect-Specific Production of New GameXPeptides in Photorhabdus luminescens TTO1, Widespread Natural Products in Entomopathogenic Bacteria

MPS-Authors

There are no MPG-Authors in the publication available

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Nollmann, F. I., Dauth, C., Mulley, G., Kegler, C., Kaiser, M., Waterfield, N. R., et al. (2015). Insect-Specific Production of New GameXPeptides in Photorhabdus luminescens TTO1, Widespread Natural Products in Entomopathogenic Bacteria. CHEMBIOCHEM, 16(2), 205-208. doi:10.1002/cbic.201402603.

Cite as: https://hdl.handle.net/21.11116/0000-000A-0508-8

Abstract

Discovery of new natural products by heterologous expression reaches its limits, especially when specific building blocks are missing in the heterologous host or the production medium. Here, we describe the insect-specific production of the new GameXPeptides E-H (5-8) from Photorhabdus luminescens TTO1, which can be produced heterologously from expression of the GameXPeptide synthetase GxpS only upon supplementation of the production media with the missing building blocks, and thus must be regarded as the true natural products under natural conditions.