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Journal Article

Myxotyrosides A and B, Unusual Rhamnosides from Myxococcus sp.

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Ohlendorf, B., Lorenzen, W., Kehraus, S., Krick, A., Bode, H. B., & Koenig, G. M. (2009). Myxotyrosides A and B, Unusual Rhamnosides from Myxococcus sp. JOURNAL OF NATURAL PRODUCTS, 72(1), 82-86. doi:10.1021/np8005875.

Cite as: https://hdl.handle.net/21.11116/0000-000A-05AC-F
Myxobacteria are gliding bacteria of the delta-subdivision of the Proteobacteria and known for their unique biosynthetic capabilities. Two examples of a new class of metabolites, myxotyrosides A (1) and B (2), were isolated from a Myxococcus sp. The myxotyrosides have a tyrosine-derived core structure glycosylated with rhamnose and acylated with unusual fatty acids such as (Z)- 15-methyl-2-hexadecenoic and (Z)-2-hexadecenoic acid. The fatty acid profile of the investigated Myxococcus sp. (strain 131) is that of a typical myxobactefium with a high similarity to those described for M. fulvus and M. xanthus, with significant concentrations of neither 15-methyl-2-hexadecenoic acid nor 2-hexadecenoic acid being detected.