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Quantification of magnetization transfer by sampling the transient signal using MT-prepared single-shot EPI

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Helms, G., & Hagberg, G. (2003). Quantification of magnetization transfer by sampling the transient signal using MT-prepared single-shot EPI. Concepts in Magnetic Resonance Part A, 19A(2), 149-152. doi:10.1002/cmr.a.10093.


Cite as: https://hdl.handle.net/21.11116/0000-000A-0FB3-C
Abstract
We describe the standard model for magnetization transfer (MT): a two-pool system with pseudo-linear exchange kinetics; under the influence of repetitive “MT-pulses” that create arbitrary instantaneous saturation. The influence of the pulse repetition period on the steady state (Part I) and the transient behavior of the system (Part II) provides similar but not equivalent information about relaxation, exchange and saturation. A quantification of all six parameters was possible by sampling the transitions and steady state at pulse repetition times between 8 ms and 200 ms by means of single-shot echo-planar imaging of the human brain in vivo.