Help Privacy Policy Disclaimer
  Advanced SearchBrowse




Meeting Abstract

Elucidating mechanisms of protein self-organization on membranes


Schwille,  Petra
Schwille, Petra / Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available

Schwille, P. (2022). Elucidating mechanisms of protein self-organization on membranes. Biophysical Journal (Annual Meeting Abstracts), 121(3, S1), 319A-319A.

Cite as: http://hdl.handle.net/21.11116/0000-000A-2ACE-0
The MinDE protein system is a paradigm for molecular self-organization and pattern formation on membranes. In spite of intense research being done on MinDE dynamics in vivo and particularly in vitro, the exact molecular mechanisms of the nonlinear association/dissociation processes between the proteins and the membrane as a catalytic surface are still unknown. We have in the past years applied high-speed atomic force microscopy, single molecule TIR microscopy, and recently also mass photometry on that system and combined it with rational protein mutagenesis. This allowed us to arrive at stunning new insights into the complex design of this self-organizing machinery, which I will summarize here. These insights may in the future inform us about how to build synthetic pattern-forming systems on membranes from the bottom-up.