Assessment of esophageal motility disorders by real-time MRI

Biggemann, L.; Uhlig, J.; Gliem, N.; Al-Bourini, O.; Wedi, E.; Ellenrieder, V.; Ghadimi, M.; Uecker, M.; Frahm, J.; Lotz, J.; Hosseini, A. S. A.; Streit, U.

doi:10.1016/j.ejrad.2020.109265

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Assessment of esophageal motility disorders by real-time MRI

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Frahm, J.
Research Group of Biomedical NMR, MPI for Biophysical Chemistry, Max Planck Society;

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Citation

Biggemann, L., Uhlig, J., Gliem, N., Al-Bourini, O., Wedi, E., Ellenrieder, V., et al. (2020). Assessment of esophageal motility disorders by real-time MRI. European Journal of Radiology. doi:10.1016/j.ejrad.2020.109265.

Cite as: https://hdl.handle.net/21.11116/0000-000A-EED3-C

Abstract

Purpose
To investigate imaging findings of esophageal motility disorders on dynamic real-time.

Material and methods
102 patients with GERD-like symptoms were included in this retrospective study between 2015−2018. Dynamic real-time MRI visualized the transit of a 10 mL pineapple juice bolus through the esophagus and EGJ with a temporal resolution of 40 ms. Dynamic and anatomic parameters were measured by consensus reading. Imaging findings were compared to HRM utilizing the Chicago classification of esophageal motility disorders, v3.0.

Results
All 102 patients completed real-time MRI in a median examination time of 15 min. On HRM, 14 patients presented with disorders with EGJ outlet obstruction (EGJOO) (13.7 %), 7 patients with major disorders of peristalsis (6.9 %), and 32 patients with minor disorders of peristalsis (31.4 %). HRM was normal in 49 patients (48.0 %). Incomplete bolus clearance was significantly more frequent in patients with esophageal motility disorders on HRM than in patients with normal HRM (p = 0.0002). In patients with motility disorders with EGJOO and major disorders of peristalsis, the esophageal diameter tended to be wider (23.6 ± 8.0 vs. 21.2 ± 3.5 mm, p = 0.089) and the sphincter length longer (19.7 ± 7.3 vs. 16.7 ± 3.0 mm, p = 0.091) compared to patients with normal HRM. 3/7 patients with achalasia type II were correctly identified by real-time MRI and one further achalasia type II patient was diagnosed with a motility disorder on MRI films. The other 3/7 patients presented no specific imaging features.

Conclusion
Real-time MRI is an auxiliary diagnostic tool for the assessment of swallowing events. Imaging parameters may assist in the detection of esophageal motility disorders.