Hierarchical folding of the catalytic core during mitochondrial ribosome 
biogenesis

Lavdovskaia, E.; Hillen, H. S.; Richter-Dennerlein, R.

doi:10.1016/j.tcb.2021.09.004

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Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis

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Hillen, H. S.
Research Group Structure and Function of Molecular Machines, Max Planck Institute for Multidisciplinary Sciences, Max Planck Society;

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Citation

Lavdovskaia, E., Hillen, H. S., & Richter-Dennerlein, R. (2022). Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis. Trends in Cell Biology, 32(3), 182-185. doi:10.1016/j.tcb.2021.09.004.

Cite as: https://hdl.handle.net/21.11116/0000-000A-B87F-9

Abstract

Final maturation steps during ribosome biogenesis require the assistance of assembly and quality control factors to ensure the folding of rRNA and proteins into a functional translation machinery. Here we integrate several recent structural snapshots of native large ribosomal subunit intermediates into the complex pathway of mitochondrial ribosome assembly.