Mitochondrien: wie die Gene im Kraftwerk der Zelle aktiviert werden

Bhatta, A.; Hillen, H.

doi:10.1007/s12268-022-1711-z

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Mitochondrien: wie die Gene im Kraftwerk der Zelle aktiviert werden

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Bhatta, A.
Research Group Structure and Function of Molecular Machines, Max Planck Institute for Multidisciplinary Sciences, Max Planck Society;

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Hillen, H.
Research Group Structure and Function of Molecular Machines, Max Planck Institute for Multidisciplinary Sciences, Max Planck Society;

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Citation

Bhatta, A., & Hillen, H. (2022). Mitochondrien: wie die Gene im Kraftwerk der Zelle aktiviert werden. BIOspektrum, 28(1), 18-22. doi:10.1007/s12268-022-1711-z.

Cite as: https://hdl.handle.net/21.11116/0000-000A-818B-7

Abstract

Mitochondria contain an organellar genome that encodes for subunits
of the respiratory chain. Its coordinated expression is essential for
eukaryotic life and defects in this process lead to severe disease. How-
ever, the molecular mechanisms underlying mitochondrial gene
expression remain poorly understood. Recent structural and functional
studies have provided the first mechanistic insights into mitochondrial
gene expression and highlight the evolutionarily unique nature of this
system.