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Mapping of weak current-induced magnetic fields in a 3D volume of the human brain at high resolution: 2D vs. Simultaneous multi slice

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Göksu,  C
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Heule,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Göksu, C., Scheffler, K., Gregersen, F., Eroğlu, H., Heule, R., Siebner, H., et al. (2022). Mapping of weak current-induced magnetic fields in a 3D volume of the human brain at high resolution: 2D vs. Simultaneous multi slice. Poster presented at Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting (ISMRM 2022), London, UK.


Cite as: http://hdl.handle.net/21.11116/0000-000A-5C48-F
Abstract
Exact knowledge of current distributions induced by transcranial electrical stimulation (TES) in the brain is important for effective clinical use of TES. MRCDI uses MRI to measure the TES-induced magnetic fields for estimating the underlying current flow distributions. The estimation methods can benefit from highly sensitive volume MRCDI measurements at a high spatial resolution. Here, we advanced our 2D spoiled gradient-echo-based MRCDI method for a sparse volume acquisition by using simultaneous-multi-slice (SMS) acquisition. Our SMS strategy demonstrated 25% improvement in noise floors against 2D. We test the performance of our methods by phantom and human in-vivo experiments using cable-loop currents.