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R2* changes reflect the kinetics of formalin-based penetration and fixation in post-mortem tissue

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Nazemorroaya,  A
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Schulz,  H
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Hagberg,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Nazemorroaya, A., Aghaeifar, A., Schulz, H., Scheffler, K., Shiozawa-Bayer, T., Hirt, B., et al. (2022). R2* changes reflect the kinetics of formalin-based penetration and fixation in post-mortem tissue. Poster presented at Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting (ISMRM 2022), London, UK.


Cite as: http://hdl.handle.net/21.11116/0000-000A-5CCB-B
Abstract
Post-mortem brain MRI can yield valuable information. However, tissue preservation requires substitution of the CSF-fluid by fixation agents, which is time-consuming for large samples. R2* maps, dominated by R2-effects, were measured at several timepoints during fixation of pig-brain tissue samples using formalin-based fixatives.