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Journal Article

Iron Deficiency Causes Wrinkles in Host-Commensal Relationships

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Clasen,  SJ
Department Microbiome Science, Max Planck Institute for Developmental Biology, Max Planck Society;

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Ley,  RE
Department Microbiome Science, Max Planck Institute for Developmental Biology, Max Planck Society;

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Citation

Clasen, S., & Ley, R. (2020). Iron Deficiency Causes Wrinkles in Host-Commensal Relationships. Cell Metabolism, 31(1), 8-10. doi:10.1016/j.cmet.2019.12.003.


Cite as: https://hdl.handle.net/21.11116/0000-000A-5E53-0
Abstract
Iron is essential for both the host and its resident microbes, resulting in competition under iron-deficient conditions. However, the molecular details underlying this competition are not fully understood. In this issue, Das et al. (2019) describe how a common gut commensal disrupts the host iron regulatory pathway to prevent uptake when iron is scarce.