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Presence and absence of type VI secretion systems in bacteria

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Pintor,  K. L.
Research Group Bacterial Secretion Systems, Department of Ecophysiology, Max Planck Institute for Terrestrial Microbiology, Max Planck Society;

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Diepold,  A.
Research Group Bacterial Secretion Systems, Department of Ecophysiology, Max Planck Institute for Terrestrial Microbiology, Max Planck Society;

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Citation

Unni, R., Pintor, K. L., Diepold, A., & Unterweger, D. (2022). Presence and absence of type VI secretion systems in bacteria. Microbiology, 168(4): 001151. doi:10.1099/mic.0.001151.


Cite as: https://hdl.handle.net/21.11116/0000-000A-62D1-B
Abstract
The type VI secretion system (T6SS) is a molecular puncturing device that enables Gram-negative bacteria to kill competitors, manipulate host cells and take up nutrients. Who would want to miss such superpowers? Indeed, many studies show how widespread the secretion apparatus is among microbes. However, it is becoming evident that, on multiple taxonomic levels, from phyla to species and strains, some bacteria lack a T6SS. Here, we review who does and does not have a type VI secretion apparatus and speculate on the dynamic process of gaining and losing the secretion system to better understand its spread and distribution across the microbial world.