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Journal Article

Proposal of a population wide genome-based testing for Covid-19


Lehrach,  Hans
Emeritus Group of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;
Alacris Theranostics GmbH, Berlin, Germany;

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Lehrach, H., Curtis, J., Lange, B., Ogilvie, L. A., Gauss, R., Steininger, C., et al. (2022). Proposal of a population wide genome-based testing for Covid-19. Scientific Reports, 12: 5618. doi:10.1038/s41598-022-08934-2.

Cite as: https://hdl.handle.net/21.11116/0000-000A-68A1-B
Our lives (and deaths) have by now been dominated for two years by COVID-19, a pandemic that has caused hundreds of millions of disease cases, millions of deaths, trillions in economic costs, and major restrictions on our freedom. Here we suggest a novel tool for controlling the COVID-19 pandemic. The key element is a method for a population-scale PCR-based testing, applied on a systematic and repeated basis. For this we have developed a low cost, highly sensitive virus-genome-based test. Using Germany as an example, we demonstrate by using a mathematical model, how useful this strategy could have been in controlling the pandemic. We show using real-world examples how this might be implemented on a mass scale and discuss the feasibility of this approach.