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Journal Article

Primary cilia mechanosensing triggers autophagy-regulated cell volume control

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Takacs,  Z
IMPRS From Molecules to Organisms, Max Planck Institute for Developmental Biology, Max Planck Society;

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Proikas-Cezanne,  T
IMPRS From Molecules to Organisms, Max Planck Institute for Developmental Biology, Max Planck Society;

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Citation

Takacs, Z., & Proikas-Cezanne, T. (2016). Primary cilia mechanosensing triggers autophagy-regulated cell volume control. Nature Cell Biology, 18(6), 591-592. doi:10.1038/ncb3366.


Cite as: https://hdl.handle.net/21.11116/0000-000A-8CFF-A
Abstract
The primary cilium and the process of autophagy are thought to be in a functionally reciprocal relationship. In further support of this link, fluid flow sensing by the primary cilium is now shown to induce autophagy, which in turn regulates the volume of kidney epithelial cells.