Help Privacy Policy Disclaimer
  Advanced SearchBrowse




Journal Article

Characterization of lipid bilayers adsorbed to functionalized air/water interfaces


Scoppola,  Ernesto       
Wolfgang Wagermaier, Biomaterialien, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)

(Publisher version), 3MB

Supplementary Material (public)
There is no public supplementary material available

Pusterla, J., Scoppola, E., Appel, C., Mukhina, T., Shen, C., Brezesinski, G., et al. (2022). Characterization of lipid bilayers adsorbed to functionalized air/water interfaces. Nanoscale, 14(40), 15048-15059. doi:10.1039/D2NR03334H.

Cite as: https://hdl.handle.net/21.11116/0000-000A-9D55-6
Lipid bilayers immobilized in planar geometries, such as solid-supported or "floating" bilayers, have enabled detailed studies of biological membranes with numerous experimental techniques, notably x-ray and neutron reflectometry. However, the presence of a solid support also has disadvantages as it complicates the use of spectroscopic techniques as well as surface rheological measurements that would require surface deformations. Here, in order to overcome these limitations, we investigate lipid bilayers adsorbed to inherently soft and experimentally well accessible air/water interfaces that are functionalized with Langmuir monolayers of amphiphiles. The bilayers are characterized with ellipsometry, X-ray scattering, and X-ray fluorescence. Grazing-incidence X-ray diffraction reveals that lipid bilayers in a chain-ordered state can have significantly different structural features than regular Langmuir monolayers of the same composition. Our results suggest that bilayers at air/water interfaces may be well suited for fundamental studies in the field of membrane biophysics.