Bio-hybrid micro-swimmers propelled by flagella isolated from C. reinhardtii

Ahmad, Raheel; Bae, Albert J.; Su, Yu-Jung; Goli Pozveh, Samira; Bodenschatz, Eberhard; Pumir, Alain; Gholami, Azam

doi:10.1039/D2SM00574C

アイテム詳細

登録内容を編集ファイル形式で保存

一時保存へ追加

タグ情報を表示リリース履歴を表示詳細要約

公開

学術論文

Bio-hybrid micro-swimmers propelled by flagella isolated from C. reinhardtii

MPS-Authors

/persons/resource/persons260068

Ahmad, Raheel
Laboratory for Fluid Physics, Pattern Formation and Biocomplexity, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

/persons/resource/persons261150

Bae, Albert J.
Laboratory for Fluid Physics, Pattern Formation and Biocomplexity, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

/persons/resource/persons269963

Su, Yu-Jung
Laboratory for Fluid Physics, Pattern Formation and Biocomplexity, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

/persons/resource/persons269965

Goli Pozveh, Samira
Laboratory for Fluid Physics, Pattern Formation and Biocomplexity, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

/persons/resource/persons173472

Bodenschatz, Eberhard
Laboratory for Fluid Physics, Pattern Formation and Biocomplexity, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

/persons/resource/persons173623

Pumir, Alain
Laboratory for Fluid Physics, Pattern Formation and Biocomplexity, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

/persons/resource/persons173518

Gholami, Azam
Laboratory for Fluid Physics, Pattern Formation and Biocomplexity, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society;

External Resource

There are no locators available

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

フルテキスト (公開)

公開されているフルテキストはありません

付随資料 (公開)

There is no public supplementary material available

引用

Ahmad, R., Bae, A. J., Su, Y.-J., Goli Pozveh, S., Bodenschatz, E., Pumir, A., & Gholami, A. (2022). Bio-hybrid micro-swimmers propelled by flagella isolated from C. reinhardtii. Soft Matter, 18, 4767-4777. doi:10.1039/D2SM00574C.

引用: https://hdl.handle.net/21.11116/0000-000A-A84A-6

要旨

Bio-hybrid micro-swimmers, composed of biological entities integrated with synthetic constructs, actively transport cargo by converting chemical energy into mechanical work. Here, using isolated and demembranated flagella from green algae Chlamydomonas reinhardtii (C. reinhardtii), we build efficient axonemally-driven micro-swimmers that consume ATP to propel micron-sized beads. Depending on the calcium concentration, we observed two main classes of motion: whereas beads move along curved trajectories at calcium concentrations below 0.03 mM, they are propelled along straight paths when the calcium concentration increases. In this regime, they reached velocities of approximately 20 μm s−1, comparable to human sperm velocity in vivo. We relate this transition to the properties of beating axonemes, in particular the reduced static curvature with increasing calcium concentration. Our designed system has potential applications in the fabrication of synthetic micro-swimmers, and in particular, bio-actuated medical micro-robots for targeted drug delivery.