English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Poster

Statistical Tests for Detecting Differential RNA-Transcript Expression from Read Counts

MPS-Authors
/persons/resource/persons84969

Stegle,  O
Department Molecular Biology, Max Planck Institute for Developmental Biology, Max Planck Society;

/persons/resource/persons75313

Borgwardt,  KM
Department Molecular Biology, Max Planck Institute for Developmental Biology, Max Planck Society;

External Resource

http://www.iscb.org/uploaded/css/68/18886.pdf
(Abstract)

Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Drewe, P., Stegle, O., Bohnert, R., Borgwardt, K., & Rätsch, G. (2010). Statistical Tests for Detecting Differential RNA-Transcript Expression from Read Counts. Poster presented at 18th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB 2010), Boston, MA, USA.


Cite as: https://hdl.handle.net/21.11116/0000-000A-DA4C-C
Abstract
We present two novel statistical tests for differential abundances of RNA
transcripts: a 'gene structure sensitive' Poisson test when the transcript structure of a gene is
known, and a kernel-based test when it is unknown.
We show that both approaches perform better than testing for differential expression by first quantifying the transcript abundance.