Metals make proteins stick

Höcker, B

doi:10.1016/j.chembiol.2010.02.002

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Metals make proteins stick

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Höcker, B
Research Group Protein Design, Max Planck Institute for Developmental Biology, Max Planck Society;

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Höcker, B. (2010). Metals make proteins stick. Chemistry & Biology, 17(2), 103-104. doi:10.1016/j.chembiol.2010.02.002.

Cite as: https://hdl.handle.net/21.11116/0000-000A-E290-3

Abstract

Salgado et al. (2009b) report the rational design of protein interfaces based on metal-mediated association. Initially coordinated via zinc, the adapted interface self-associates, even in the absence of metal. The approach is hypothesized to mimic the early evolution of protein assemblies.