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Multi-parameter mapping with 500 µm resolution using a flexible 23-channel RF coil

MPS-Authors
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Pine,  Kerrin
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

/persons/resource/persons198956

Vaculciakova,  Lenka
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

/persons/resource/persons180061

Kirilina,  Evgeniya
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

/persons/resource/persons201756

Scherf,  Nico
Method and Development Group Neural Data Science and Statistical Computing, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

/persons/resource/persons147461

Weiskopf,  Nikolaus
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Multi-Parameter Mapping with 500 µm Resolution Using a Flexible 23-Channel RF Coil
(Abstract)

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Citation

Pine, K., Vaculciakova, L., Kirilina, E., Scherf, N., & Weiskopf, N. (2018). Multi-parameter mapping with 500 µm resolution using a flexible 23-channel RF coil. In Proceedings of the Joint Annual Meeting ISMRM-ESMRMB 2018.


Cite as: https://hdl.handle.net/21.11116/0000-000A-E98B-3
Abstract
To better understand the human brain’s microstructure, there is a need for in-vivo myelin and iron mapping methods which have sufficient resolution to map mesoscopic intra-cortical structures (e.g. lamina). However, resolution is critically SNR-limited. We show that by using a mechanically flexible RF coil array which conforms to the subject’s own individual skull shape, sufficient SNR is gained to map the main MR contrast parameters and the line of Gennari within the superficial primary visual cortex. The work demonstrates the feasibility of laminar analysis of myelination at widely available modest field strengths.