Absolute optical chiral analysis using cavity-enhanced polarimetry

Bougas, Lykourgos; Byron, Joseph; Budker, Dmitry; Williams, Jonathan

doi:10.1126/sciadv.abm3749

アイテム詳細

登録内容を編集ファイル形式で保存

一時保存へ追加

タグ情報を表示リリース履歴を表示詳細要約

公開

学術論文

Absolute optical chiral analysis using cavity-enhanced polarimetry

MPS-Authors

/persons/resource/persons230541

Byron, Joseph
Atmospheric Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons101364

Williams, Jonathan
Atmospheric Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

External Resource

https://www.science.org/doi/epdf/10.1126/sciadv.abm3749
(出版社版)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

フルテキスト (公開)

公開されているフルテキストはありません

付随資料 (公開)

There is no public supplementary material available

引用

Bougas, L., Byron, J., Budker, D., & Williams, J. (2022). Absolute optical chiral analysis using cavity-enhanced polarimetry. Science Advances, 8(22):. doi:10.1126/sciadv.abm3749.

引用: https://hdl.handle.net/21.11116/0000-000A-FC37-D

要旨

Chiral analysis is central for scientific advancement in the fields of chemistry, biology, and medicine. It is also indispensable in the development and quality control of chiral compounds in the chemical and pharmaceutical industries. Here, we present the concept of absolute optical chiral analysis, as enabled by cavity-enhanced polarimetry, which allows for accurate unambiguous enantiomeric characterization and enantiomeric excess determination of chiral compounds within complex mixtures at trace levels, without the need for calibration, even in the gas phase. Our approach and technology enable the absolute postchromatographic chiral analysis of complex gaseous mixtures, the rapid quality control of complex mixtures containing chiral volatile compounds, and the online in situ observation of chiral volatile emissions from a plant under stress.