DENTIST-using long reads for closing assembly gaps at high accuracy.

Ludwig, Arne; Pippel, Martin; Myers, Gene; Hiller, Michael

doi:10.1093/gigascience/giab100

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

DENTIST-using long reads for closing assembly gaps at high accuracy.

MPS-Authors

/persons/resource/persons246904

Pippel, Martin
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

/persons/resource/persons219475

Myers, Gene
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

/persons/resource/persons184581

Hiller, Michael
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Ludwig, A., Pippel, M., Myers, G., & Hiller, M. (2022). DENTIST-using long reads for closing assembly gaps at high accuracy. GigaScience, 11: giab100. doi:10.1093/gigascience/giab100.

Cite as: https://hdl.handle.net/21.11116/0000-000B-0333-8

Abstract

Long sequencing reads allow increasing contiguity and completeness of fragmented, short-read-based genome assemblies by closing assembly gaps, ideally at high accuracy. While several gap-closing methods have been developed, these methods often close an assembly gap with sequence that does not accurately represent the true sequence.