Stem cell-derived β cells go in monkeys.

Grapin-Botton, Anne; Ludwig, Barbara

doi:10.1016/j.stem.2022.03.010

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Stem cell-derived β cells go in monkeys.

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Grapin-Botton, Anne
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Grapin-Botton, A., & Ludwig, B. (2022). Stem cell-derived β cells go in monkeys. Cell stem cell, 29(4), 500-502. doi:10.1016/j.stem.2022.03.010.

Cite as: https://hdl.handle.net/21.11116/0000-000B-0389-7

Abstract

Du et al. transplanted β cells derived from pluripotent stem cells in diabetic monkeys for the first time, as an intermediate stage toward clinical translation. They observed benefits unfolding over months but also observed immune rejection of the grafts by 5-6 months.