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Recent Advances Reached by Combining Ultralow-Field Magnetic Resonance and Hyperpolarization Techniques

MPS-Authors
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Kempf,  N
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Fehling,  P
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Engelmann,  J
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons252847

Boldt,  J
Fine Mechanical Workshop, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Steffen,  T
Electronical Workshop, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Beyerlein,  M
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Pohmann,  R       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84187

Scheffler,  K       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Buckenmaier,  K       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Kempf, N., Pravdivtsev, A., Plaumann, M., Körber, R., Myers, J., Fehling, P., et al. (2022). Recent Advances Reached by Combining Ultralow-Field Magnetic Resonance and Hyperpolarization Techniques. Poster presented at Ampere NMR School 2022, Zakopane, Poland.


Cite as: https://hdl.handle.net/21.11116/0000-000B-321F-B
Abstract
Ultralow-field nuclear magnetic resonance promises new opportunities for magnetic
resonance spectroscopy and imaging. Here we present a Superconducting QUantum
Interference Device (SQUID) based MR system. There are several methods to increase the
instrinsic low SNR at ultralow-fields. For example: prepolarization, ParaHydrogen-Induced
Polarization (PHIP) or Overhauser Dynamic Nuclear Polarization (ODNP) [1]. Our recent
efforts have further enhanced 15 N polarization through novel and substrate optimized
sequences [2]; enabled in-vivo imaging with ODNP; and could provide bio-compatible
hyperpolarized substrates based on parahydrogen techniques.