The role of the gut microbiome during host ageing

Seidel, J.; Valenzano, D. R.

doi:10.12688/f1000research.15121.1

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

The role of the gut microbiome during host ageing

MPS-Authors

/persons/resource/persons281678

Seidel, J.
Valenzano – Evolutionary and Experimental Biology of Ageing, Max Planck Research Groups, Max Planck Institute for Biology of Ageing, Max Planck Society;

/persons/resource/persons278157

Valenzano, D. R.
Valenzano – Evolutionary and Experimental Biology of Ageing, Max Planck Research Groups, Max Planck Institute for Biology of Ageing, Max Planck Society;

External Resource

https://www.ncbi.nlm.nih.gov/pubmed/30057748
(Any fulltext)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Seidel, J., & Valenzano, D. R. (2018). The role of the gut microbiome during host ageing. F1000Res, 7. doi:10.12688/f1000research.15121.1.

Cite as: https://hdl.handle.net/21.11116/0000-000B-446C-0

Abstract

Gut microbial communities participate in key aspects of host biology, including development, nutrient absorption, immunity and disease. During host ageing, intestinal microbes undergo dramatic changes in composition and function and can shift from commensal to pathogenic. However, whether they play a causal role in host ageing and life span has remained an open question for a long time. Recent work in model organisms has revealed for the first time that gut microbes can modulate ageing, opening new questions and opportunities to uncover novel ageing-modulating mechanisms and to design anti-ageing interventions by targeting the gut microbiota.