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Conference Paper

Quantification of transverse relaxation times in vivo at 7T field-strength

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Schmidt,  Jochen
International Max Planck Research School on Neuroscience of Communication: Function, Structure, and Plasticity, MPI for Human Cognitive and Brain Sciences, Max Planck Society;
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Scheibe,  Patrick       
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Weiskopf,  Nikolaus       
Felix Bloch Institute for Solid State Physics, Faculty of Physics and Earth Sciences, Leipzig University;
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Trampel,  Robert       
Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Citation

Schmidt, J., Radunsky, D., Scheibe, P., Ben-Eliezer, N., Weiskopf, N., & Trampel, R. (2021). Quantification of transverse relaxation times in vivo at 7T field-strength. In Proceedings of the ISMRM & SMRT Annual Meeting & Exhibition.


Cite as: https://hdl.handle.net/21.11116/0000-000B-5527-A
Abstract
Accurate quantification of transverse relaxation times in vivo is of vital importance for research and clinical applications. At higher field-strength, the gain in signal enables T2 mapping at sub-millimetre resolutions, but with infeasible scan time for standard spin-echo techniques. Using CPMG echo trains reduces the acquisition time. However, inhomogeneities of the transmit B1 field hamper accurate T2 quantification. Correcting for resulting bias effects is possible through signal response simulations via the Bloch equations using the specific sequence parameters. Matching acquired data to the simulated signal points allows accurate and robust fitting of T2 values as shown by 7T study.